A few words about the biochemical action of Inositol

More specifically, inositol is known as vitamin B8, a natural isomer of glucose. It is an important key intermediate of the second messengers, but also a dominant component of cell membrane phospholipids involved in many biological processes.

It is a component of the biological information exchange system.

Inositol contributes to the processing of information within the cell, e.g. of biological information contained in hormones. The second messengers are molecules inside cells that act to transmit signals from a receptor to a target. The term, second messengers, was coined by the invention of these substances to distinguish them from hormones and other molecules that function outside the cell as "first messengers" in the transmission of biological information. A large number of molecules have been identified as second messengers, including phospholipid-derived molecules (inositol triphosphate).

A general mechanism -system- of a second messenger can be divided into four stages.

First stage: the agonist activates a receptor bound to the membrane.
Second stage: activated protein G produces a basic operator.
Third stage: the main effect stimulates the composition of the second messenger.
Fourth stage: the second messenger activates a certain cellular process.
G-protein-binding receptors for the messenger PIP2 (phosphatidylinositol diphosphate) system produce two effectors, phospholipase C (PLC) and phosphoinositide 3-kinase (P3K). The PLC as an operator produces two different second messengers, inositol triphosphate (IP3) and diacylglycerol (DAG).

IP3 (inositol triphosphate) is soluble and diffuses freely into the cytoplasm. As a second messenger, it is recognized by the inositol triphosphate receptor (IP3R), a Ca2 + channel in the endoplasmic reticulum (ER) membrane that stores intracellular Ca2 +.

Binding of (inositol triphosphate) IP3 to its receptor releases Ca2 + from the endoplasmic reticulum into the normally normal Ca2 +-deficient cytoplasm, which then activates the signaling of various Ca2 + manifestations. Specifically in blood vessels, increasing the Ca2 + concentration by (inositol triphosphate) IP3 releases nitric oxide, which then diffuses into the smooth muscle tissue and causes relaxation.

In 1984, in a paper published in Nature, inositol triphosphate was officially classified as the second cellular messenger. By 2010 the volume of the bibliography exceeds 20,000 publications in many scientific journals.

Its role starts in biology, is involved in medicine (in specialties such as neurology, endocrinology and pathology), and is realized in pharmacy.

EOF Notification Number: 16897 / 15-02-2016

(The Notification Number to the EOF is not a marketing authorization from the EOF)

WARNINGS:
• Do not exceed the recommended daily dose.
• S / D should not be used as a substitute for a balanced diet.
• Keep out of the reach of small children.
• This product is not intended to prevent, treat or cure any human disease.
• Check with your doctor if you are pregnant, breast-feeding, taking medication or have any health problems.

Dosage
1 - 2 tablets / day